HU JianDirector

Department :

Thoracic Surgery

Languages :

Chinese, English

Biography

As a thoracic surgeon for more than 30 years, Dr. Hu have devoted his clinical practice to diagnosing and treating patients with lung cancer, esophageal cancer, mesothelioma, and all other cancers of the chest cavity. In addition to serving as Chief of Thoracic Surgery, He is  the Program Director of the Cardiothoracic Surgery Program at Zhejiang University.

He was one of the first thoracic surgeons in the China to develop expertise in minimally invasive or VATS/Robotic approaches, and as such the overwhelming majority of his patients with lung or esophageal cancer receive the benefits of this approach. In his role(s) at The First Affiliated Hospital of Zhejiang University, He is committed to continuing to enhance the quality of care and the outcomes for all patients who receive thoracic surgery at our institution. We understand that each patient is unique, and therefore he strives to design patient-specific treatment approaches that leverage the unique expertise of our  thoracic surgery program.  

His research focuses on the molecular mechanisms governing the development of metastases in patients with early-stage lung, esophageal cancer and mediastinal tumors. In addition, his team has been a pioneer in exploring the clinical application of newly developed surgical devices for patients with lung cancers that will be removed by minimally invasive manner. We are interested in understanding how to best integrate molecular characterization of lung and esophageal cancers, and minimally invasive surgical approaches to all thoracic malignancies.

 


Interests

Minimally invasive treatment for thoracic malignancy and other disorders

Achalasia

Airway Management And Surgery

Barrett's Esophagus

Benign Esophageal Disease And Surgery

COPD

Emphysema

Empyema

Esophageal Cancer

Gastroesophageal Reflux Disease (GERD)

Germ Cell Tumor

Hernia Management

Lung Cancer

Lung Cancer Screening

Lung Infection

Lung Nodules

Lung Transplantation

Lymphoma

Medical Education

Mesothelioma

Minimally Invasive Surgery

Neurogenic Tumor

Pectus Malformation

Pleural Effusion

Pneumothorax

Post-Operative Management

Pulmonary Sarcoidosis

Quality Improvement

Rib Fractures

Swallowing Problems

Thoracic Outlet Syndrome

Thymoma And Thymic Cancer

Tracheal Disorders


Activities and Honors

Director, Department of Thoracic Surgery, The First Affiliated Hospital of Zhejiang University

Professor of Surgery, School of Medicine, Zhejiang University

Director of Cardiothoracic Surgery Program, School of Medicine, Zhejiang University

President, Medical Association of Zhejiang Province, General Thoracic Surgery Group(since 2019)

Committee Member of Chinese Society of Thoracic Surgery

Core Committee Member of Chinese Society of Thoracic Surgery, Robotic Surgery Group

Core Committee Member of Chinese Society of Thoracic Surgery, Minimally Invasive Surgery Group


Professional Memberships

1. Zhang Y#, Chen C#, Hu J#, Han Y, Huang M, Xiang J, Li H*. Early outcomes of robotic versus thoracoscopic segmentectomy for early-stage lung cancer: A multi-institutional propensity score-matched analysis. J Thorac Cardiovasc Surg. 2020 Jan 25. pii: S0022-5223(20)30226-9.

2. Cao L, Yuan X, Bao F, Lv W, He Z, Tang J, Han J, Hu J*. Downregulation of HSPA2 inhibits proliferation via ERK1/2 pathway and endoplasmic reticular stress in lung adenocarcinoma. Ann Transl Med. 2019 Oct;7(20):540.

3. Wu X, Wang Y, Lin X, Wang Z, Xu J, Lv W, Hu J*. Racial and Ethnic Disparities in Lung Adenocarcinoma Survival: A Competing-Risk Model. Clin Lung Cancer. 2019 Oct 25. pii: S1525- 7304(19)30289-X.

4. Wu Y, Xu J, Du C, Wu Y, Xia D, Lv W, Hu J*. The Predictive Value of Tumor Mutation Burden on Efficacy of Immune Checkpoint Inhibitors in Cancers: A Systematic Review and Meta- Analysis. Front Oncol. 2019 Nov 5;9:1161.

5. Yuan P, Huang S, Bao FC, Cao JL, Sheng HX, Shi L, Lv W, Hu J*. Discriminating association of a common telomerase reverse transcriptase promoter polymorphism with telomere parameters in non-small cell lung cancer with or without epidermal growth factor receptor mutation. Eur J Cancer. 2019 Oct;120:10-19.

6. Wu Y, Yang R, Xu J, Rusidanmu A, Zhang X, Hu J*. Effects of Intraoperative Fluid Management on Postoperative Outcomes After Lobectomy. Ann Thorac Surg. 2019 Jun;107(6):1663-1669.

7. Fang L, Wang L, Wang Y, Wu Y, Ye P, Lv W, Hu J*. Predictors and survival impact of station 4L metastasis in left non-small cell lung cancer. J Cancer Res Clin Oncol. 2019 May;145(5):1313-1319.

8. Zhu L, Xu H, Lv W, He Z, Ye P, Wang Y, Hu J*. miR-199b-5p Regulates Immune-Mediated Allograft Rejection after Lung Transplantation Through the GSK3β and NF-κB Pathways. Inflammation. 2018 Aug;41(4):1524-1535.

9. Cao J, Xu J, He Z, Yuan P, Huang S, Lv W, Hu J*. Prognostic impact of lymphadenectomy on outcomes of sublobar resection for stage IA non-small cell lung cancer ≤2 cm. J Thorac Cardiovasc Surg. 2018 Aug;156(2):796-805.

10. Cao J, Lv W, Wang L, Xu J, Yuan P, Huang S, He Z, Hu J*. Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways.Cell Death Dis. 2018 Jul 26;9(8):817.

11. Cao J, Yuan P, Wang Y, Xu J, Yuan X, Wang Z, Lv W, Hu J*. Survival Rates After Lobectomy, Segmentectomy, and Wedge Resection for Non-Small Cell Lung Cancer. Ann Thorac Surg. 2018 May;105(5):1483-1491.

12. Zhou Z, Wang Z, Zheng Z, Cao J, Zhang C, He Z, Lv W, Hu J*. An "alternative finger" in robotic-assisted thoracic surgery: intraoperative ultrasound localization of pulmonary nodules. Med Ultrason. 2017 Nov 29;19(4):374-379.

13. Yuan P, Cao JL, Huang S, Zhang C, Bao FC, Hu YJ, Lv W, Hu J*. Sublobar Resection for Pulmonary Aspergilloma: A Safe Alternative to Lobectomy. Ann Thorac Surg. 2017 Jun;103(6):1788-1794.

14. Tu ZL, Zhou ZY, Xu HC, Cao JL, Ye P, Wang LM, Lv W, Hu J*. LTB4 and montelukast in transplantation-related bronchiolitis obliterans in rats. J Cardiothorac Surg. 2017 May 25;12(1):43.

15. Jin C, Cao J, Cai Y, Wang L, Liu K, Shen W, Hu J. A nomogram for predicting the risk of invasive pulmonary adenocarcinoma for patients with solitary peripheral subsolid nodules. J Thorac Cardiovasc Surg. 2017 Feb;153(2):462-469.

16. Meng D, Zhou Z, Wang Y, Wang L, Lv W, Hu J*. Lymphadenectomy for clinical early-stage non-small-cell lung cancer: a systematic review and meta-analysis. Eur J Cardiothorac Surg. 2016 Oct;50(4):597-604.

17. Cao J, Yuan P, Ma H, Ye P, Wang Y, Yuan X, Bao F, Lv W, Hu J*. Log Odds of Positive Lymph Nodes Predicts Survival in Patients After Resection for Esophageal Cancer. Ann Thorac Surg. 2016 Aug;102(2):424-32.

18. Zhu YC, Xu CW, Ye XQ, Yin MX, Zhang JX, Du KQ, Zhang ZH, Hu J*. Lung cancer with concurrent EGFR mutation and ROS1 rearrangement: a case report and review of the literature. Onco Targets Ther. 2016 Jul 15;9:4301-5.

19. Bao F, Zhang C, Yang Y, He Z, Wang L, Hu J*. Comparison of robotic and video-assisted thoracic surgery for lung cancer: a propensity-matched analysis. J Thorac Dis. 2016 Jul;8(7):1798-803.

20. Bao F, Abuduwufuer A, Yuan X, Lv X, Hu J*. Optimal Lung Cancer Candidates for Sublobar Resection: Prediction of Pathologic Node-Negative Clinical Stage IA NSCLC. Ann Thorac Surg. 2015 Jun;99(6):2253.

21. Sun F, Chen T, Han J, Ye P, Hu J*. Staging accuracy of endoscopic ultrasound for esophageal cancer after neoadjuvant chemotherapy: a meta-analysis and systematic review. Dis Esophagus. 2015 Nov-Dec;28(8):757-71.

22. Bao F, Yuan P, Yuan X, Lv X, Wang Z, Hu J*. Predictive risk factors for lymph node metastasis in patients with small size non-small cell lung cancer. J Thorac Dis. 2014 Dec;6(12):1697-703.

23. Yang Y, Bao F, He Z, Hu J*. Single-port video-assisted thoracoscopic right upper lobectomy using a flexible videoscope. Eur J Cardiothorac Surg. 2014 Sep;46(3):496-7.

24. Bao F, Ye P, Yang Y, Wang L, Zhang C, Lv X, Hu J*. Segmentectomy or lobectomy for early stage lung cancer: a meta-analysis. Eur J Cardiothorac Surg. 2014 Jul;46(1):1-7.

25. Xu HC, Ye P, Bao FC, Pan H, Yang YH, Wang LM, Wang ZT, Li ZB, He ZH, Han WL, Wang YQ, Hu J*. ECMO-assisted esophagectomy after left pneumonectomy. Int J Artif Organs. 2013 Apr;36(4):259-62.